| Title: | Integrated Filtration Bioanalyzer |
| Patent Number: | 9,068,976 |
| Application Number: | 12/582,392 |
| Filed: | October 20, 2009 |
| Issued: | June 30, 2015. Term adjustment 685 days. |
| Official Filing: | View the Complete Patent at the US Patent & Trademark Office |
| Abstract: | The present invention relates to an in vitro assay method and device that provides for detection and measurement of entities in a fluid sample that can be captured and concentrated in a unitized self-contained enclosed filter apparatus that is analyzed in an optical detection instrument for indications of the entity. It provides for analysis of biological material including cells, their enzymes, or other constituents thereof, that can be identified based on an indicator-generating means. The analysis provided for include detection of the presence of the entity, and changes in the entity over time, such as associated with growth and increasing metabolic activity with an expanding population of cells, or decreasing metabolic activity, for example, due to presence of inhibitory or toxic agents. |
| Title: | Filtered Assay Device and Method |
| Patent Number: | 8,968,681 |
| Application Number: | 12/582,425 |
| Filed: | October 20, 2009 |
| Issued: | March 3, 2015. Term adjustment 496 days. |
| Official Filing: | View the Complete Patent at the US Patent & Trademark Office |
| Abstract: | A method and device is provided for collecting filterable material to perform assays on a filtration apparatus by applying negative-pressure to the inlet chamber of the filtration apparatus which is independent of negative or positive pressure applied to its fluid path. The negative-pressure applied to the inlet chamber serves to actively aspirate fluid and promote flow into the inlet chamber via the fluid pathway. The negative-pressure applied to the inlet chamber facilitates the use of either negative or positive-pressure based fluid-filtration approaches. Use of the invention improves the functionality and scope of applications that can be performed with enclosed filtration apparatuses. |
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